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- Salif Keita
- Sallie Ford
- Samba Touré
- Sandra Hall
- Sandra N'Kaké
- Sanseverino
- Santana
- Sarah Lancman
- Sarah McCoy
- Sarah McKenzie
- Saron Crenshaw
- Saul Rubin
- Saunn et Starr
- Scorpions
- Scott Colley
- Seasick Steve
- Sébastien Texier
- Sekou Kouyaté
- Sekouba Bambino
- Selwyn Birchwood
- Seun Kuti
- Shabaka Hutchings
- Shahin Novrasli
- Shaï Maestro
- Shakura S'Aïda
- Sharde Thomas
- Sharon Jones
- Shawn Holt
- Shemekia Copeland
- Shuggie Otis
- Sidiki Diabaté
- Sly Johnson
- Snarky Puppy
- Solomon Burke
- Songhoy Blues
- Sonny Landreth
- Sonny Rollins
- Sonny Simmons
- Sophie Alour
- Spencer Bohren
- Spyro Gyra
- Stacey Kent
- Stagger Lee
- Stanley Clarke
- Stefano Di Battista
- Stefon Harris
- Stéphane Belmondo
- Stéphane Guillaume
- Stéphane Huchard
- Stéphane Kerecki
- Steve Coleman
- Steve Cropper
- Steve Smith
- Steve Swallow
- Steve Van Zandt
- Steve Verbeke
- Steve'n'Seagulls
- Steven Troch Band
- Stochelo Rosenberg
- Sue Foley
- Sugaray Rayford
- Sullivan Fortner
- Sun Râ Arkestra
- Susan Tedeschi
- Susie Ibarra
- Sylvain Luc
- Sylvaine Hélary